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Septal myectomy

Relieving obstruction in hypertrophic cardiomyopathy

In obstructive hypertrophic cardiomyopathy (HCM), thickened heart muscle blocks blood leaving the heart. A septal myectomy removes part of that muscle to restore flow.

Surgical loupes and operating light

Watch: in my words

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What is hypertrophic cardiomyopathy, and what does a myectomy do?

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Myectomy, alcohol septal ablation or newer medicines — how I think about the options

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Who needs a myectomy

Myectomy is usually recommended when HCM symptoms persist despite medication, or when the thickening into the left ventricle is severe. It’s also considered for women with HCM who want to become pregnant, even without severe symptoms.

What to expect

The operation takes about three to four hours. Recovery starts in the ICU, walking with a physical therapist begins around 48 hours after surgery, and most people go home in fewer than five days. Symptom relief comes over days to weeks, and energy usually returns to normal within a few weeks.

94%

had symptom improvement after surgery in one study

Fewer than 5 days

typical hospital stay

Sources for this section: Cleveland Clinic — Septal myectomy

Common questions

When are medicines enough?

Many people with HCM are managed with medicines. Myectomy is usually recommended when symptoms persist despite them or the obstruction is severe.

Source: Cleveland Clinic — Septal myectomy

What tests will I need before surgery?

Typically blood tests, an echocardiogram, an EKG, a chest X-ray, a cardiac MRI and a cardiac catheterization.

Source: Cleveland Clinic — Septal myectomy

What are the risks?

Myectomy is generally low-risk. Possible complications include fluid around the heart or lungs, atrial fibrillation and heart block (a disruption of the heart’s electrical signals that can require a pacemaker). Risk is higher with other heart conditions, tobacco use, or age over 65.

Source: Cleveland Clinic — Septal myectomy

I’m thinking about pregnancy — does that change the timing?

It can. Myectomy is considered for women with HCM who want to become pregnant, even without severe symptoms. Talk with us and your cardiologist before you plan a pregnancy.

Source: Cleveland Clinic — Septal myectomy

Should my family be screened for HCM?

HCM can run in families. Northwestern Medicine recommends that adult first-degree relatives — parents, siblings and children — see a physician for an ECG and echocardiogram, repeated every five years. If your genetic mutation is identified, relatives can be tested with a blood sample.

Source: Northwestern Medicine — Family screening for HCM

Sources

  1. Cleveland Clinic — Septal myectomy
  2. Northwestern Medicine — Family screening for HCM

This page is general education, not medical advice. Your own care depends on your anatomy, your health and your goals — the reason we talk it through together. Reviewed by Jeremy Leidenfrost, MD, cardiothoracic surgeon, October 2026.

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