MyHeartSurgery.ai

Mitral valve-in-valve

A new valve inside a worn-out one

When a tissue mitral valve from an earlier operation wears out, a new valve can often be placed inside it through a vein — avoiding a second open-heart operation.

Dr. Leidenfrost’s heart surgery team at work

Watch: in my words

Coming soon

Mechanical or tissue valve — how I help patients choose

New videos are being recorded now. Captions will be included.

How it works

A catheter goes from a vein in the leg into the heart, crossing the wall between the upper chambers (a “transseptal” approach). The new valve expands inside the old one and takes over its job.

What the national data show

In 1,529 U.S. patients who received a balloon-expandable valve inside a failed surgical mitral valve (STS/ACC TVT Registry), the procedure was technically successful in 96.8% of cases. With the transseptal approach, mortality was 5.0% at 30 days and 15.8% at one year in this older, higher-risk group, with lasting improvement in heart-failure symptoms.

96.8%

technical success

5.0%

30-day mortality, transseptal approach, in an older, higher-risk group

Planning ahead

Whether valve-in-valve is possible depends on the size and type of your original valve. That’s one reason the first valve choice matters: a valve chosen with a future valve-in-valve in mind keeps more options open.

Sources for this section: JAMA, 2020 — mitral valve-in-valve, STS/ACC TVT Registry · TCTMD — valve-in-valve durability and planning ahead (2020)

Common questions

Who is a candidate?

Patients whose tissue mitral valve from an earlier operation has worn out. Suitability depends on the original valve’s size and type, so we review your prior operative report and imaging together.

Source: JAMA, 2020 — mitral valve-in-valve, STS/ACC TVT Registry

Is it better than a second open operation?

For many patients it avoids reopening the chest, but not for everyone. The heart team weighs your anatomy, age and health against a redo surgical replacement.

Source: JAMA, 2020 — mitral valve-in-valve, STS/ACC TVT Registry · TCTMD — valve-in-valve durability and planning ahead (2020)

What results can I expect?

In the national registry, the procedure was technically successful in 96.8% of patients, with lasting improvement in heart-failure symptoms. Those patients were older and higher-risk, so your own risk may differ.

Source: JAMA, 2020 — mitral valve-in-valve, STS/ACC TVT Registry

Sources

  1. JAMA, 2020 — mitral valve-in-valve, STS/ACC TVT Registry
  2. TCTMD — valve-in-valve durability and planning ahead (2020)

This page is general education, not medical advice. Your own care depends on your anatomy, your health and your goals — the reason we talk it through together. Reviewed by Jeremy Leidenfrost, MD, cardiothoracic surgeon, October 2026.

Consultations and second opinions

Talk with Dr. Leidenfrost

Whether you’ve just been diagnosed or have already been told you need surgery, I’m glad to review your case and talk through your options — including a second opinion on a recommendation you’ve received.

Call (314) 434-3049

Monday–Friday, 8 a.m.–4 p.m. Central

  1. 1 · Call our office

    Tell our office you’d like a consultation or a second opinion.

  2. 2 · We gather your records

    Your records, imaging and prior tests — we do the chasing, not you.

  3. 3 · An honest assessment

    Whether surgery is right, whether a less invasive option exists, and what realistic outcomes look like.

  4. 4 · Your decision

    Take it wherever you want — to us, to your current doctor, or home to your family.